The song is the duo's first top 10 since "Little Black Submarines" in 2012.
For the first time in six years, The Black Keys rank in the top 10 of Billboard's Hot Rock Songs chart.
The duo collects its sixth Hot Rock Songs top 10 on the March 23-dated list with "Lo/Hi," which vaults 34-5 following its first full week of streaming, sales and radio airplay tracking.
The song follows the act's most recent top 10, "Little Black Submarines," which hit No. 6 in October 2012, and is its first top five hit since "Gold on the Ceiling" (No. 2 that June).
"Lo/Hi," the first single from The Black Keys' upcoming ninth studio album, surges with 2.3 million U.S. streams and 8,000 downloads sold, according to Nielsen Music. It also breaks into the top five of the Rock Airplay chart (No. 4; 7.2 million impressions) and the top 10 on the Adult Alternative Songs (No. 6) and Alternative Songs (No. 9) airplay tallies.
The track debuts at No. 4 on Rock Digital Song Sales, the twosome's best rank, surpassing the No. 7 debut and peak of "Fever" in April 2014.
The buzz surrounding "Lo/Hi" is due in large part to it being the first new music from Dan Auerbach and Patrick Carney together as The Black Keys since 2014's Turn Blue, which opened at No. 1 on the Billboard 200. The act has since been mostly on hiatus, with each member recording projects either solo or with others, as well as producing others' records.
A release date for the follow-up to Turn Blue has not yet been announced.