Malone and Scott venture onto the rock ranking for the first time after scoring success on a variety of charts, largely in the R&B, rap and pop formats.
The song's bow echoes rap chart staple Machine Gun Kelly having made Mainstream Rock Songs as featured on Motley Crue's "The Dirt (Est. 1981)," which hit No. 8 in April.
Osbourne appears on Mainstream Rock Songs for the first time as a solo artist since "Let It Die," which peaked at No. 21 in February 2011. Overall, he had charted most recently as part of Black Sabbath, whose "End of the Beginning" reached No. 38 in August 2013.
"Take What You Want," from Post Malone's second Billboard 200 No. 1, Hollywood's Bleeding, debuted at its No. 8 high on the Billboard Hot 100 dated Sept. 21. The song, at No. 25 in its third week, brought Osbourne back to the top 10 for the first time since 1989.